孕甾-4-烯-17Alpha,21-二醇-3,20-二酮-21-醋酸酯合成路线 （共 52 条）
反应条件
2: (N,N-dimethylamino)pyridine, pyridine 3: 92 percent / PdCl2(CH3CN)2 / tetrahydrofuran / Ambient temperature 4: 1. KOH, 2.) N-bromoacetamide View Scheme
参考文献
Journal of Organic Chemistry, , vol. 58, # 11 p. 2929 - 2930
反应条件
1: 92 percent / PdCl2(CH3CN)2 / tetrahydrofuran / Ambient temperature 2: 1. KOH, 2.) N-bromoacetamide View Scheme
参考文献
Journal of Organic Chemistry, , vol. 58, # 11 p. 2929 - 2930
反应条件
triethylamine in acetone 5 h; HeatingInert atmosphere;
参考文献
Claudel, Emilie; Arbez-Gindre, Cecile; Berl, Valerie; Lepoittevin, Jean-Pierre
Synthesis, 2009 , # 20 p. 3391 - 3398
反应条件
semicarbazide-hydrochloride; sodium acetate; acetic acid Erwaermen des Reaktionsgemisches mit Brenztraubensaeure und Natriumacetat unter Zusatz von Wasser;
参考文献
Journal of the American Chemical Society, , vol. 71, p. 3262
Journal of the American Chemical Society, , vol. 73, p. 189,192
反应条件
1: acetic acid; bromine 2: 2.4-dinitro-phenylhydrazine; sodium acetate; acetic acid / Erwaermen des Reaktionsgemisches mit Brenztraubensaeure unter Zusatz von Chloroform und Wasser View Scheme
参考文献
Journal of the American Chemical Society, , vol. 71, p. 3262
Journal of the American Chemical Society, , vol. 73, p. 189,192
反应条件
1: 1.) DMAP, Et3N, 2.) lithium diisopropylamide (LDA) / 1.) THF, 2.) hexane, from -80 deg C to -30 deg C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 112, # 17 p. 6449 - 6450
反应条件
potassium permanganate; N-benzyl-N,N,N-triethylammonium chloride in dichloromethane Ambient temperature;
参考文献
Gumulka, Maria; Kurek, Alicja; Wicha, Jerzy
Polish Journal of Chemistry, 1982 , vol. 56, # 4-6 p. 741 - 748
反应条件
chromium(VI) oxide; water; acetic acid T=11°C;
参考文献
Journal of Biological Chemistry, , vol. 162, p. 601,6307
反应条件
1: aq. KHCO3 / methanol View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 15 p. 774 - 775
反应条件
1: 92 percent / p-TsOH / CH2Cl2 / 1.5 h / Ambient temperature 2: 67 percent / diisobutylaluminium hydride / CH2Cl2; hexane / 0.5 h / -78 °C 3: 83 percent / pyridine / Ambient temperature 4: 95 percent / p-TsOH, MeOH / 0.05 h / 50 °C 5: 77 percent / aluminium isopropoxide / toluene; cyclohexanone / 20 h / Heating 6: 28 percent / KMnO4, triethylbenzylammonium chloride (TEBACl) / CH2Cl2 / Ambient temperature View Scheme
参考文献
Polish Journal of Chemistry, , vol. 56, # 4-6 p. 741 - 748
