1: With sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in toluene T=62 - 75°C; 5 h; Inert atmosphere; 2: With hydrogenchloride in tert-butyl methyl ether; water; toluene Cooling with ice-water; 3: With sodium hydroxide in tert-butyl methyl ether; water pH=13; Cooling with ice-water;

1: With formic acid; palladium on activated charcoal in ethanol Inert atmosphereHeating; 2: With sodium hydroxide in chloroform; water pH=~ 12; Cooling with ice-water;