反应条件
1: Et3N / CH2Cl2 / 0.17 h / 0 °C
2: NaI / dimethylformamide / 1 h / 110 °C
3: N-chlorosuccinimide (NCS) / CCl4 / Ambient temperature
4: 1.) NaH / 1.) THF, 0 deg C, 0.5 h, 2.) THF, RT, 24 h
5: 14 percent / TMEDA, sec-BuLi / tetrahydrofuran; cyclohexane / 1.) -85 deg C, 1 h, 2.) RT, 12 h
View Scheme
参考文献
Harada, Toshiro; Karasawa, Akio; Oku, Akira
Journal of Organic Chemistry, 1986 , vol. 51, # 6 p. 842 - 846
