3-环己烯-1-羧酸甲酯合成路线 （共 53 条）
反应条件
1: 75 percent / aq. NaOH / benzene / 20 h / Ambient temperature 2: 80 percent / H2SO4 / 24 h / Heating 3: 70 percent / NaBH4 / methanol / 4 h / 0 °C 4: 60 percent / pyridine / 1.) 0 deg C, 1 h, 2.) room temperature, 3 h 5: LiI, HMPA / 150 °C View Scheme
参考文献
Synthetic Communications, , vol. 14, # 5 p. 401 - 406
反应条件
1: 70 percent / NaBH4 / methanol / 4 h / 0 °C 2: 60 percent / pyridine / 1.) 0 deg C, 1 h, 2.) room temperature, 3 h 3: LiI, HMPA / 150 °C View Scheme
参考文献
Synthetic Communications, , vol. 14, # 5 p. 401 - 406
反应条件
1: 80 percent / H2SO4 / 24 h / Heating 2: 70 percent / NaBH4 / methanol / 4 h / 0 °C 3: 60 percent / pyridine / 1.) 0 deg C, 1 h, 2.) room temperature, 3 h 4: LiI, HMPA / 150 °C View Scheme
参考文献
Synthetic Communications, , vol. 14, # 5 p. 401 - 406
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; lithium iodide T=150°C;
参考文献
Synthetic Communications, , vol. 14, # 5 p. 401 - 406
反应条件
sulfuric acid T=125°C;
参考文献
Zhurnal Obshchei Khimii, , vol. 17, p. 2231
Chem.Abstr., , p. 4957
反应条件
1: hydrogenchloride / water / 6 h / 20 °C / Reflux 2: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 18 h / 20 - 120 °C View Scheme
参考文献
EP2368870 A1, ;
EP 2368870 A1
反应条件
1: 60 percent / pyridine / 1.) 0 deg C, 1 h, 2.) room temperature, 3 h 2: LiI, HMPA / 150 °C View Scheme
参考文献
Synthetic Communications, , vol. 14, # 5 p. 401 - 406
反应条件
toluene-4-sulfonic acid; hydroquinone 1.) 150 deg C, 24 h, 2.) benzene, reflux, 0.5 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2415 - 2434
反应条件
1.) ether, room temperature, 1 h, 2.) 150 deg C, 24 h; Yield given. Multistep reaction;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2415 - 2434
参考文献
Journal of the American Chemical Society, , vol. 79, p. 3098,3101
