[5-[(哌啶-1-基)羰基]-1H-苯并咪唑-2-基]氨基甲酸甲酯合成路线 （共 6 条）
反应条件
1: SOCl2 / benzene / 4 h / Heating
2: Et3N / benzene / 2 h / Ambient temperature
3: 70 percent / 10percent aq. NaOH / ethanol / 1 h / Ambient temperature
4: hydrazine hydrate / Raney Ni / ethanol / 1 h / Heating
5: 25percent aq. NaOH, AcOH / ethanol / 1 h
View Scheme
参考文献
Kumar; Seth; Bhaduri; Visen; Misra; Gupta; Fatima; Katiyar; Chatterjee; Sen
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 1083 - 1089
反应条件
1: 70 percent / 10percent aq. NaOH / ethanol / 1 h / Ambient temperature
2: hydrazine hydrate / Raney Ni / ethanol / 1 h / Heating
3: 25percent aq. NaOH, AcOH / ethanol / 1 h
View Scheme
参考文献
Kumar; Seth; Bhaduri; Visen; Misra; Gupta; Fatima; Katiyar; Chatterjee; Sen
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 1083 - 1089
反应条件
1: 80 percent / HNO3 / 1 h / 0 °C
2: SOCl2 / benzene / 4 h / Heating
3: Et3N / benzene / 2 h / Ambient temperature
4: 70 percent / 10percent aq. NaOH / ethanol / 1 h / Ambient temperature
5: hydrazine hydrate / Raney Ni / ethanol / 1 h / Heating
6: 25percent aq. NaOH, AcOH / ethanol / 1 h
View Scheme
参考文献
Kumar; Seth; Bhaduri; Visen; Misra; Gupta; Fatima; Katiyar; Chatterjee; Sen
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 1083 - 1089
反应条件
1: hydrazine hydrate / Raney Ni / ethanol / 1 h / Heating
2: 25percent aq. NaOH, AcOH / ethanol / 1 h
View Scheme
参考文献
Kumar; Seth; Bhaduri; Visen; Misra; Gupta; Fatima; Katiyar; Chatterjee; Sen
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 1083 - 1089
反应条件
sodium hydroxide; acetic acid in ethanol
1 h; Yield given;
参考文献
Kumar; Seth; Bhaduri; Visen; Misra; Gupta; Fatima; Katiyar; Chatterjee; Sen
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 1083 - 1089
参考文献
Palomares-Alonso, Francisca; Jung-Cook, Helgi; Perez-Villanueva, Jaime; Piliado, Juan Carlos; Rodriguez-Morales, Sergio; Palencia-Hernandez, Guadalupe; Lopez-Balbiaux, Nayeli; Hernandez-Campos, Alicia; Castillo, Rafael; Hernandez-Luis, Francisco
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 4 p. 1794 - 1800
