2-(4-甲基苯基)-2-氧代乙酸乙酯合成路线 （共 36 条）
反应条件
1: 1-(iodo)-4-methylbenzene With isopropylmagnesium chloride in tetrahydrofuran T=20 - 30°C; 1.16667 h; Inert atmosphere; 2: With zinc(II) chloride in tetrahydrofuran T=0 - 20°C; Inert atmosphere; 3: α-acetoxyacetyl chloride With copper(l) chloride in tetrahydrofuran T=30°C; Inert atmosphere;
参考文献
McLaughlin, Mark; Belyk, Kevin M.; Qian, Gang; Reamer, Robert A.; Chen, Cheng-Yi
Journal of Organic Chemistry, 2012 , vol. 77, # 11 p. 5144 - 5148
反应条件
triethylamine in acetone
参考文献
Sakuragi, Hirochika; Koyama, Toshiya; Sakurazawa, Mamoru; Yasui, Norimichi; Tokumaru, Katsumi; Ueno, Katsuhiko
Bulletin of the Chemical Society of Japan, 1994 , vol. 67, # 6 p. 1769 - 1772
反应条件
1: AlCl3 / CH2Cl2 2: acetonitrile / 3 h / Heating View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 14, # 24 p. 3861 - 3866
参考文献
Bulletin of the Chemical Society of Japan, , vol. 32, p. 960,961
Journal of the American Chemical Society, , vol. 73, p. 4230,4231
反应条件
in acetic acid T=70°C; 2 h; Further byproducts given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1087 - 1094
反应条件
in acetic acid T=70°C; 2 h; Yield given. Further byproducts given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1087 - 1094
反应条件
1: 1) 2M BuLi in cyclohexane / 1) THF, -78 deg C, 2 h, 2) THF, -78 deg C, 4 h then RT, overnight 2: 86 percent / p-TsOH / 24 h / 90 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 36, # 6 p. 841 - 844
反应条件
in acetonitrile 3 h; Heating;
参考文献
Tetrahedron Asymmetry, , vol. 14, # 24 p. 3861 - 3866
反应条件
acetic anhydride; acetic acid
参考文献
Bulletin of the Chemical Society of Japan, , vol. 51, p. 335 - 336
参考文献
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 128, p. 313
