1: anhydrous 1-octyne With Schwartz's reagent in tetrahydrofuran
T=20°C; 1 h;
2: 3,3-dimethyl-2-phenylsulphonyloxirane With lithium diisopropyl amide in tetrahydrofuran; n-heptane; ethylbenzene
T=-90 - -60°C; 1 h;
3: With oxygen; sodium hydrogencarbonate in tetrahydrofuran; various solvents; water
T=20°C; 1 h;
参考文献
Kasatkin, Aleksandra; Whitby, Richard J.
Tetrahedron, 2003 , vol. 59, # 49 p. 9857 - 9864
1.1: LDA / tetrahydrofuran; hexane / 1 h / -78 °C
1.2: tetrahydrofuran; hexane / -78 °C
2.1: 10.6 g / CeCl3*7H2O; NaI / acetonitrile / 3 h / Heating
View Scheme
参考文献
Palomo, Claudio; Oiarbide, Mikel; Halder, Rajkumar; Kelso, Michael; Gomez-Bengoa, Enrique; Garcia, Jesus M.
Journal of the American Chemical Society, 2004 , vol. 126, # 30 p. 9188 - 9189
1.1: LDA / tetrahydrofuran; hexane / 1 h / -78 °C
1.2: tetrahydrofuran; hexane / -78 °C
2.1: 10.6 g / CeCl3*7H2O; NaI / acetonitrile / 3 h / Heating
View Scheme
参考文献
Palomo, Claudio; Oiarbide, Mikel; Halder, Rajkumar; Kelso, Michael; Gomez-Bengoa, Enrique; Garcia, Jesus M.
Journal of the American Chemical Society, 2004 , vol. 126, # 30 p. 9188 - 9189
