1-[(2S)-吡咯烷甲基]哌啶合成路线 （共 12 条）
反应条件
1: 78 percent / NaIO4, RuO2 / H2O; ethyl acetate / 0.5 h / 0 °C
2: 1.) trifluoroacetic acid (TFA), 2.) 2 M aq. NaOH / 1.) CHCl3, reflux, 24 h, 2.) 90 deg C, 1 h
View Scheme
参考文献
Alker; Doyle; Harwood; McGregor
Tetrahedron Asymmetry, 1990 , vol. 1, # 12 p. 877 - 880
反应条件
sodium hydroxide; trifluoroacetic acid
1.) CHCl3, reflux, 24 h, 2.) 90 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Alker; Doyle; Harwood; McGregor
Tetrahedron Asymmetry, 1990 , vol. 1, # 12 p. 877 - 880
