反应条件
1: 2-bromo-4-pyridinecarboxylic acid With tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether Inert atmosphere; 2: 3,4,5-trimethoxyphenylboronic acid With potassium carbonate in ethylene glycol dimethyl ether; water T=95°C; Inert atmosphere;
参考文献
Jansen, Koen; Heirbaut, Leen; Verkerk, Robert; Cheng, Jonathan D.; Joossens, Jurgen; Cos, Paul; Maes, Louis; Lambeir, Anne-Marie; De Meester, Ingrid; Augustyns, Koen; Van Der Veken, Pieter
Journal of Medicinal Chemistry, 2014 , vol. 57, # 7 p. 3053 - 3074