1-(4-甲氧基苯氧基)-2-丙酮合成路线 （共 8 条）
反应条件
1: aq. NaOH 3: H2 / Pt 4: (i) aq. NaNO2, aq. HCl, (ii) aq. H3PO2 View Scheme
参考文献
Govindachari,T.R. et al.
Indian Journal of Chemistry, 1966 , vol. 4, p. 433 - 437
反应条件
oxygen; lithium chloride; copper dichloride; {Pd2(MeCN)2(PHT)[(S)-Tol-BINAP]}(BF4)2 in tetrahydrofuran; water
T=25°C; P=760 Torr; Title compound not separated from byproducts;
参考文献
El-Qisairi, Arab K; Qaseer, Hanan A; Henry, Patrick M
Journal of Organometallic Chemistry, 2002 , vol. 656, # 1-2 p. 168 - 176
反应条件
potassium carbonate; acetone; potassium iodide
参考文献
Sublett; Calaway
Journal of the American Chemical Society, 1948 , vol. 70, p. 674
反应条件
dirhodium tetraacetate in dichloromethane
T=20°C; 12 h; Kinetics; Further Variations:Reagents;
参考文献
Qu, Zhaohui; Shi, Weifeng; Wang, Jianbo
Journal of Organic Chemistry, 2004 , vol. 69, # 1 p. 217 - 219
反应条件
1: 87 percent / K2CO3 / acetone / 2 h / Heating
2: O2; LiCl; CuCl2 / {Pd2(MeCN)2(PHT)[(S)-Tol-BINAP]}(BF4)2 / tetrahydrofuran; H2O / 25 °C / 760 Torr
View Scheme
参考文献
El-Qisairi, Arab K; Qaseer, Hanan A; Henry, Patrick M
Journal of Organometallic Chemistry, 2002 , vol. 656, # 1-2 p. 168 - 176
反应条件
1: NH2OH*HCl / pyridine / 3 h / Heating
2: LiAlH4 / diethyl ether / 12 h / Heating
View Scheme
参考文献
Leclerc; Decker; Schwartz
Arzneimittel-Forschung/Drug Research, 1985 , vol. 35, # 9 p. 1357 - 1367
反应条件
hydroxylamine hydrochloride in pyridine
3 h; Heating;
参考文献
Leclerc; Decker; Schwartz
Arzneimittel-Forschung/Drug Research, 1985 , vol. 35, # 9 p. 1357 - 1367
反应条件
1.1: 64 percent / sodium cyanoborohydride; HCl; molecular sieves 4 Angstroem / ethanol / 72 h / 20 °C
2.1: 32 percent / K2CO3 / ethanol / 72 h / 110 °C
3.1: hydrogen chloride / benzene / 0.25 h / 0 °C
3.2: 15 percent / SOCl2 / benzene / 8 h / Heating
View Scheme
参考文献
Giardina, Dario; Crucianelli, Mauro; Angeli, Piero; Buccioni, Michela; Gulini, Ugo; Marucci, Gabriella; Sagratini, Gianni; Melchiorre, Carlo
Bioorganic and medicinal chemistry, 2002 , vol. 10, # 5 p. 1291 - 1303
