反应条件
1: 73 percent / potassium permanganate / H2O; ethanol / 1.) -10 deg C, 1 h, 2.) to 40 deg C, 10 min 2: 86 percent / imidazole / dimethylformamide / 2 h / Ambient temperature 3: 1.) lead tetraacetate, 2.) Red-Al / 1.) benzene, pyridine, 25 deg C, 10 min, 2.) water, 1,5h 4: 91 percent / N-chlorosuccinimide, dimethyl sulfide / 1.) CH2Cl2, -20 deg C, 30 min, 2.) 0 deg C, 30 min 5: 1.) n-butyllithium, 2.) 5percent H2O2 / 1.) hexane, THF,-50 deg C, 15 min, 2.) chloroform, 1 min View Scheme
参考文献
Toh, H. T.; Okamura, William H.
Journal of Organic Chemistry, 1983 , vol. 48, # 9 p. 1414 - 1417
