1-苯基-2-丁炔-1-酮合成路线 （共 27 条）
反应条件
1: diethyl ether
2: CrO3
View Scheme
参考文献
Curtin; Crump
Journal of the American Chemical Society, 1958 , vol. 80, p. 1922,1925
反应条件
PhCH2Pd(PPh3)2Cl in acetonitrile-D3
react. of Sb compd. with acid chloride in the presence of Pd-catalyst;
参考文献
Yamamoto, Yohsuke; Okinaka, Takaaki; Nakatani, Masayuki; Akiba, Kin-ya
Nippon Kagaku Kaishi (Journal of the Chemical Society of Japan), 1987 , vol. 62, p. 1286 - 1287
反应条件
1: 1,2-dibromo-propane With lithium diisopropyl amide in tetrahydrofuran; hexane
T=-78 - 0°C;
2: N-Methoxy-N-methyl-benzamide in tetrahydrofuran; hexane
T=-78 - 20°C;
3: With hydrogenchloride in tetrahydrofuran; hexane; water
T=0°C;
参考文献
Tanaka, Yuta; Kanai, Motomu; Shibasaki, Masakatsu
Journal of the American Chemical Society, 2010 , vol. 132, # 26 p. 8862 - 8863
反应条件
in 1,2-dichloro-benzene
Heating;
参考文献
Ohmori, Hidenobu; Maeda, Hatsuo; Tamaoka, Mie; Masui, Masaichiro
Chemical and Pharmaceutical Bulletin, 1988 , vol. 36, # 2 p. 613 - 620
反应条件
n-butyllithium; zinc(II) chloride; tetrakis(triphenylphosphine) palladium(0)
1.) THF, hexane, -20 deg C, 15 min, 0 deg C, 15 min, 2.) THF, 0 deg C, 30 min; Yield given. Multistep reaction;
参考文献
Suffert, Jean; Toussaint, Dominique
Journal of Organic Chemistry, 1995 , vol. 60, # 11 p. 3550 - 3553
反应条件
in 1,4-dioxane
T=70 - 80°C; 0.0833333 h;
参考文献
Fetter; Nagy; Giang; Kajtar-Peredy; Rockenbauer; Korecz; Czira
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 9 p. 1131 - 1139
反应条件
in 1,4-dioxane
T=70 - 80°C; 0.0833333 h;
参考文献
Fetter; Nagy; Giang; Kajtar-Peredy; Rockenbauer; Korecz; Czira
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 9 p. 1131 - 1139
反应条件
1: 77 percent / NaH / tetrahydrofuran / 5 h / Heating
2: 25 percent / NaN3; AlCl3 / tetrahydrofuran / 60 h / Heating
3: 42 percent / dioxane / 0.08 h / 70 - 80 °C
View Scheme
参考文献
Fetter; Nagy; Giang; Kajtar-Peredy; Rockenbauer; Korecz; Czira
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 9 p. 1131 - 1139
反应条件
1: 25 percent / NaN3; AlCl3 / tetrahydrofuran / 60 h / Heating
2: 42 percent / dioxane / 0.08 h / 70 - 80 °C
View Scheme
参考文献
Fetter; Nagy; Giang; Kajtar-Peredy; Rockenbauer; Korecz; Czira
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 9 p. 1131 - 1139
反应条件
in acetic acid
T=80°C; 0.166667 h;
参考文献
Fetter; Nagy; Giang; Kajtar-Peredy; Rockenbauer; Korecz; Czira
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 9 p. 1131 - 1139
