1-甲氧基-1H-吲哚-3-甲醛合成路线 （共 38 条）
反应条件
sodium methylate in methanol
T=75°C; 2 h;
参考文献
Yamada, Fumio; Shinmyo, Daisuke; Somei,Masanori
Heterocycles, 1994 , vol. 38, # 2 p. 273 - 276
反应条件
in water; N,N-dimethyl-formamide
参考文献
Yamada, Fumio; Fukui, Yoshikazu; Shinmyo, Daisuke; Somei, Masanori
Heterocycles, 1993 , vol. 35, # 1 p. 99 - 104
反应条件
1: 1.) NaOMe / 1.) MeOH, RT, 10 min, 2.) MeOH, reflux, 15 min
2: 56 percent / methanol / 0.25 h / Heating
View Scheme
参考文献
Somei, Masanori; Yamada, Fumio; Yamamura, Gaku
Chemical and Pharmaceutical Bulletin, 1998 , vol. 46, # 2 p. 191 - 198
反应条件
sodium hydride in N,N-dimethyl-formamide
17 h; Ambient temperature;
参考文献
Yamada, Fumio; Shinmyo, Daisuke; Nakajou, Masahiro; Somei, Masanori
Heterocycles, 2012 , vol. 86, # 1 p. 435 - 453
反应条件
sodium hydride in N,N-dimethyl-formamide
6 h; Ambient temperature;
参考文献
Yamada, Fumio; Shinmyo, Daisuke; Nakajou, Masahiro; Somei, Masanori
Heterocycles, 2012 , vol. 86, # 1 p. 435 - 453
反应条件
sodium hydride in N,N-dimethyl-formamide
6 h; Ambient temperature;
参考文献
Yamada, Fumio; Shinmyo, Daisuke; Somei,Masanori
Heterocycles, 1994 , vol. 38, # 2 p. 273 - 276
反应条件
1: piperazine With sodium hydride in N,N-dimethyl-formamide
T=20°C; 1 h; Cooling with ice;
2: daikon-phytoalexin in N,N-dimethyl-formamide
T=60°C; 3 h; regioselective reaction;
参考文献
Yamada, Fumio; Shinmyo, Daisuke; Nakajou, Masahiro; Somei, Masanori
Heterocycles, 2012 , vol. 86, # 1 p. 435 - 453
反应条件
1: methanol; daikon-phytoalexin With sodium
T=20°C; 0.0833333 h; Cooling with ice;
2: daikon-phytoalexin 2 h; Reflux; regioselective reaction;
参考文献
Yamada, Fumio; Shinmyo, Daisuke; Nakajou, Masahiro; Somei, Masanori
Heterocycles, 2012 , vol. 86, # 1 p. 435 - 453
反应条件
1: 1-methyl-piperazine With sodium hydride in N,N-dimethyl-formamide
T=20°C; 1 h; Cooling with ice;
2: daikon-phytoalexin in N,N-dimethyl-formamide
T=65°C; 1 h; regioselective reaction;
参考文献
Yamada, Fumio; Shinmyo, Daisuke; Nakajou, Masahiro; Somei, Masanori
Heterocycles, 2012 , vol. 86, # 1 p. 435 - 453
反应条件
1: 1,1-dimethylallyl alcohol With potassium hydride in N,N,N',N',N'',N''-hexamethylphosphoric triamide
T=20°C; 0.166667 h;
2: daikon-phytoalexin in N,N,N',N',N'',N''-hexamethylphosphoric triamide
T=20°C; 1 h; regioselective reaction;
参考文献
Yamada, Fumio; Shinmyo, Daisuke; Nakajou, Masahiro; Somei, Masanori
Heterocycles, 2012 , vol. 86, # 1 p. 435 - 453
