2-羟基-4-甲氧基苯甲醛合成路线 （共 227 条）
参考文献
Chemische Berichte, , vol. 80, p. 469,472
参考文献
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 58, p. 795
Chem. Zentralbl., , vol. 98, # I p. 1125
参考文献
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 58, p. 795
Chem. Zentralbl., , vol. 98, # I p. 1125
反应条件
nachfolgend Zersetzung mit Wasser;
参考文献
Justus Liebigs Annalen der Chemie, , vol. 357, p. 373
Chemische Berichte, , vol. 31, p. 1767
Chemische Berichte, , vol. 55, p. 928
反应条件
nachfolgend Kochen mit Wasser;
参考文献
Chemische Berichte, , vol. 58, p. 1702
反应条件
1: 7-hydroxy-coumarine / N,N-diethylaniline / 2 h / 210 °C 2: AlCl3, aluminium chloride / toluene / 3 h / Reflux 3: pyridine / dichloromethane / 1 h / -10 °C / Inert atmosphere View Scheme
参考文献
Starcevic, Stefan; Brozic, Petra; Turk, Samo; Cesar, Jozko; Lanisnik Rizner, Tea; Gobec, Stanislav
Journal of Medicinal Chemistry, 2011 , vol. 54, # 1 p. 248 - 261
反应条件
potassium carbonate in N,N-dimethyl-formamide T=40°C; 5 h; Inert atmosphere;
参考文献
Hu, Chunqi; Li, Xin; Wang, Weisi; Zhang, Lei; Tao, Lulu; Dong, Xiaowu; Sheng, Rong; Yang, Bo; Hu, Yongzhou
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 18 p. 5454 - 5461
反应条件
potassium carbonate in N,N-dimethyl-formamide 12 h; Heating;
参考文献
Van Veldhuizen, Joshua J.; Gillingham, Dennis G.; Garber, Steven B.; Kataoka, Osamu; Hoveyda, Amir H.
Journal of the American Chemical Society, 2003 , vol. 125, # 41 p. 12502 - 12508
反应条件
1.1: potassium carbonate; tetra(n-butyl)ammonium hydrogensulfate / dichloromethane; water / 20 °C 2.1: hydrogen; 10 Pd/C / ethyl acetate / 20 °C / 750.08 Torr 3.1: trimethylaluminum / dichloromethane; hexane / 0 - 20 °C / |Inert atmosphere 3.2: |Inert atmosphere 4.1: (R)-3,3′-bis[3,5-bis(trifluoromethyl)phenyl]-1,1′-binaphthyl-2,2′-diyl hydrogenphosphate / cyclohexane / 60 h / 20 °C / |Molecular sieve 5.1: hydrogen / acetone View Scheme
参考文献
Lee, Ji-Woong; List, Benjamin
Journal of the American Chemical Society, 2012 , vol. 134, # 44 p. 18245 - 18248
反应条件
potassium hydroxide; potassium carbonate in ethanol; water
参考文献
Takeda Chemical Industries, Ltd.
Patent: US6235771 B1, 2001 ;
