1-(3-乙基苯基)环己烷-1-醇合成路线 （共 2 条）
反应条件
1: 1-bromo-3-ethylbenzene With magnesium; iodine in tetrahydrofuran
2 h; Heating / reflux;
2: cyclohexanone in tetrahydrofuran
T=0°C; 3.5 h;
参考文献
ELAN PHARMACEUTICALS, INC.
Patent: WO2005/70407 A1, 2005 ;
Location in patent: Page/Page column 153-154 ;
WO 2005/070407 A1
反应条件
1: 1-bromo-3-ethylbenzene With iodine; magnesium in tetrahydrofuran
2 h; Heating / reflux;
2: cyclohexanone in tetrahydrofuran
T=0°C; 3.5 h;
3: With water in tetrahydrofuran
参考文献
ELAN PHARMACEUTICALS, INC.; PHARMACIA and UP JOHN COMPANY
Patent: WO2005/95326 A2, 2005 ;
Location in patent: Page/Page column 116 ;
WO 2005/095326 A2
