(S)-2-氨基-3-羟基丙酰胺合成路线 (共 4 条)
参考文献
Chemische Berichte, , vol. 91, p. 150,155
Journal fuer Praktische Chemie (Leipzig), , vol. <4> 8, p. 339,342
反应条件
1: With pyridine; di-tert-butyl dicarbonate; ammonium hydrogen carbonate in 1,4-dioxane
T=20°C; 16 h;
2: With trifluoroacetic acid
T=20°C; 0.5 h;
参考文献
RIB-X PHARMACEUTICALS, INC.
Patent: WO2005/12270 A2, 2005 ;
Location in patent: Page/Page column 64; 65 ;
参考文献
Bernhard,S.A. et al.
Journal of the American Chemical Society, 1962 , vol. 84, p. 2421 - 2434
反应条件
palladium
Hydrogenation;
参考文献
Smith; Spackman
Journal of Biological Chemistry, 1955 , vol. 212, p. 271,291