1-甲基-4-硝基-1H-吡咯-2-羧酸叔丁酯合成路线 （共 5 条）
反应条件
sulfuric acid in diethyl ether
T=20°C; 36 h;
参考文献
Kumar, Rohtash; Lown, J William
Organic and biomolecular chemistry, 2003 , vol. 1, # 15 p. 2630 - 2647
反应条件
in tert-butyl alcohol
5 h; Heating;
参考文献
Wurtz, Nicholas R.; Turner, James M.; Baird, Eldon E.; Dervan, Peter B.
Organic Letters, 2001 , vol. 3, # 8 p. 1201 - 1203
反应条件
1: HNO3; H2SO4 / acetic anhydride
2: 94.6 percent / 2-methyl-propan-2-ol / 5 h / Heating
View Scheme
参考文献
Wurtz, Nicholas R.; Turner, James M.; Baird, Eldon E.; Dervan, Peter B.
Organic Letters, 2001 , vol. 3, # 8 p. 1201 - 1203
反应条件
1: 100 percent / 80 °C
2: NaOH / tetrahydrofuran; methanol / 20 °C
3: 82 percent / H2SO4 / diethyl ether / 36 h / 20 °C
View Scheme
参考文献
Kumar, Rohtash; Lown, J William
Organic and biomolecular chemistry, 2003 , vol. 1, # 15 p. 2630 - 2647
反应条件
1: NaOH / tetrahydrofuran; methanol / 20 °C
2: 82 percent / H2SO4 / diethyl ether / 36 h / 20 °C
View Scheme
参考文献
Kumar, Rohtash; Lown, J William
Organic and biomolecular chemistry, 2003 , vol. 1, # 15 p. 2630 - 2647
