(S)-(-)-4-羟基-2-吡咯烷酮合成路线 (共 11 条)
反应条件
4-(N,N-dimethlyamino)pyridine
参考文献
Daiso Co., Ltd.
Patent: US5869694 A1, 1999 ;
反应条件
ammonia in methanol T=70°C;
参考文献
Konda; Takahashi; Onda
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 3 p. 1083 - 1087
反应条件
palladium 10 on activated carbon; hydrogen in methanol T=25°C;
参考文献
Bisol, Tula B.; Bortoluzzi, Adailton J.; Sa, Marcus M.
Journal of Organic Chemistry, 2011 , vol. 76, # 3 p. 948 - 962
反应条件
hydrogenchloride in water; acetonitrile 0.0833333 h;
参考文献
Pellegata; Pinza; Pifferi; Gaiti; Mozzi; Tirillini; Porcellati
Farmaco, Edizione Scientifica, 1981 , vol. 36, # 10 p. 845 - 855
反应条件
in N,N-dimethyl-formamide
反应条件
aluminum oxide in pyridine; toluene 24 h; Heating;
参考文献
Blade-Font, Artur
Tetrahedron Letters, 1980 , vol. 21, p. 2443 - 2446
反应条件
in anhydrous xylene Reflux;
参考文献
Organic Process Research and Development, , vol. 6, # 4 p. 416 - 418
反应条件
sodium hydrogencarbonate in pyridine; methanol; ethyl acetate
参考文献
Sankyo Company, Limited
Patent: US5424306 A1, 1995 ;
反应条件
triphenylphosphine in tetrahydrofuran
参考文献
Sankyo Company, Limited
Patent: US5424306 A1, 1995 ;
反应条件
triphenylphosphine; diethylazodicarboxylate Mitsunobu reaction;
参考文献
Seki, Masahiko; Yamanaka, Takeshi; Kondo, Kazuhiko
Journal of Organic Chemistry, 2000 , vol. 65, # 2 p. 517 - 522