2-甲基-1H-咪唑并[4,5-b]吡啶合成路线 （共 8 条）
反应条件
1: T=135 - 140°C; Inert atmosphere; 2: With ammonia in water pH=~ 10 - 12;
参考文献
MASSACHUSETTS INSTITUTE OF TECHNOLOGY; PRESIDENT AND FELLOWS OF HARVARD COLLEGE; GENZYME CORPORATION
Patent: WO2009/137081 A2, 2009 ;
Location in patent: Page/Page column 39-40 ;
WO 2009/137081 A2
反应条件
silica supported fluoroboric acid T=80°C; 0.5 h; Neat (no solvent);
参考文献
Patil, Abasaheb V.; Bandgar, Babasaheb P.; Lee, Soo-Hyoung
Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 6 p. 1719 - 1722
反应条件
tetrachlorosilane; triethylamine in dichloromethane T=110°C; 0.25 h; Microwave irradiation;
参考文献
Tetrahedron Letters, , vol. 50, # 27 p. 3798 - 3800
反应条件
lithium bromide T=110 - 115°C; 8 h; Neat (no solvent);
参考文献
Dekhane, Deepak V.; Pawar, Shivaji S.; Gupta, Sunil V.; Shingare, Murlidhar S.; Thore, Shivaji N.
Chinese Chemical Letters, 2010 , vol. 21, # 5 p. 519 - 523
反应条件
in acetic acid 15 h; Heating;
参考文献
Essassi, E. M.; Zniber, R.; Bernardini, A.; Viallefont, Ph.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1015 - 1018
反应条件
1: 60 percent / 1 h / Heating 2: 50 percent / acetic acid / 15 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 20, p. 1015 - 1018
反应条件
1: tin; hydrochloric acid View Scheme
参考文献
Chemische Berichte, , vol. 60, p. 775
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 59, p. 417
参考文献
Chemische Berichte, , vol. 60, p. 775
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 59, p. 417
Yakugaku Zasshi, , vol. 66, p. Ausg. B, S. 75
Chem.Abstr., , p. 112
