Owen
Current Science, 1943 , vol. 12, p. 228
Chem.Abstr., 1944 , p. 2006
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Owen; Ramage; Simonsen
Journal of the Chemical Society, 1938 , p. 1214
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Arndt; Loewe; Avan
Chemische Berichte, 1940 , vol. 73, p. 607
1: N-methyl-N-nitrosourea With potassium hydroxide in diethyl ether; water
2: 4-fluorophenylacetic acid chloride in diethyl ether
T=0 - 20°C; 0.5 h;
3: With hydrogen bromide in diethyl ether; water
T=-30 - 20°C; 1 h;
参考文献
SHIONOGI and CO., LTD.
Patent: EP1422218 A1, 2004 ;
Location in patent: Page 124 ;