(E)-十二碳-3-烯-1-醇合成路线 （共 11 条）
反应条件
lithium aluminium tetrahydride in diethylene glycol dimethyl ether
T=100°C; 8 h;
参考文献
Doolittle, Robert E.; Patrick, Delrea G.; Heath, Robert H.
Journal of Organic Chemistry, 1993 , vol. 58, # 19 p. 5063 - 5066
反应条件
lithium aluminium tetrahydride in diethyl ether
参考文献
Pawar, A. S.; Chattopadhyay, S.; Mamdapur, V. R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 4 p. 463 - 464
反应条件
1: 87 percent / piperidinium acetate / dimethylsulfoxide / 100 °C
2: 82 percent / Na[(CH3OCH2CH2O)2]AlH2 / diethyl ether / 2 h / 25 °C
View Scheme
参考文献
Ragoussis, Valentine; Vamvaka, Ekaterini; Kolymbadi, Maria
Journal of Chemical Research - Part S, 2002 , # 8 p. 398 - 399
反应条件
1: benzene / 5 h / Heating
2: benzene / 12 h, RT; 4 h, reflux
3: LiAlH4 / bis-(2-methoxy-ethyl) ether; tetrahydrofuran / 140 °C
View Scheme
参考文献
Pop, Lidia; Oprean, I.; Barabas, A.; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1986 , vol. 328, # 5/6 p. 867 - 878
反应条件
1: 1) Li / 1) THF, reflux, 2) DMSO, 60 - 65 deg C, 3h
2: LiAlH4 / bis-(2-methoxy-ethyl) ether; tetrahydrofuran / 140 °C
View Scheme
参考文献
Pop, Lidia; Oprean, I.; Barabas, A.; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1986 , vol. 328, # 5/6 p. 867 - 878
反应条件
1: benzene / 12 h, RT; 4 h, reflux
2: LiAlH4 / bis-(2-methoxy-ethyl) ether; tetrahydrofuran / 140 °C
View Scheme
参考文献
Pop, Lidia; Oprean, I.; Barabas, A.; Hodosan, F.
Journal fuer Praktische Chemie (Leipzig), 1986 , vol. 328, # 5/6 p. 867 - 878
反应条件
1: hydrogenchloride / benzene
2: 4,4'-di-tert-butylbiphenyl; lithium / tetrahydrofuran / 0 - 20 °C
View Scheme
参考文献
Lorber, Katja; Schieberle, Peter; Buettner, Andrea
Journal of Agricultural and Food Chemistry, 2014 , vol. 62, # 5 p. 1025 - 1031
反应条件
1: triethylamine; hydrogenchloride / 3 h / 80 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 - 20 °C
View Scheme
参考文献
Lorber, Katja; Schieberle, Peter; Buettner, Andrea
Journal of Agricultural and Food Chemistry, 2014 , vol. 62, # 5 p. 1025 - 1031
反应条件
ammonia; lithium; iron nitrate (III)
1.) THF, reflux, 100 min, 2.) THF, reflux, 135 min; Yield given. Multistep reaction;
参考文献
Patterson, John W.
Synthesis, 1985 , # 3 p. 337 - 339
反应条件
copper(l) iodide
1.) Et2O/Me2S/n-hexane, -10 deg C, 30 min; 2.) Et2O, 0 deg C, 5 h; Yield given. Multistep reaction;
参考文献
Fujisawa, Tamotsu; Kurita, Yoshitsugu; Kawashima, Masatoshi; Sato, Toshio
Chemistry Letters, 1982 , p. 1641 - 1642
