hydrogen; palladium on activated charcoal in ethanol T=50°C; P=3750.3 Torr; 48 h;

hydrogen; palladium on activated charcoal in ethanol T=50°C; P=3750.3 Torr; 48 h;

1: With tetrafluoroboric acid; iodobenzene; 3-chloro-benzenecarboperoxoic acid in dichloromethane; water T=25°C; Hofmann rearrangement; 48 h; Inert atmosphere; 2: With hydrogenchloride in dichloromethane; water Inert atmosphere;

1: 95 percent / p-TsOH / toluene / 8 h / Heating 2: 80 percent / H2 / Raney-Ni / ethanol / 240 h / 35 °C / 3750.3 Torr 3: 90 percent / H2 / 10percent Pd/C / ethanol / 48 h / 50 °C / 3750.3 Torr View Scheme

1: 80 percent / H2 / Raney-Ni / ethanol / 240 h / 35 °C / 3750.3 Torr 2: 90 percent / H2 / 10percent Pd/C / ethanol / 48 h / 50 °C / 3750.3 Torr View Scheme

1: 80 percent / H2 / Raney-Ni / ethanol / 240 h / 35 °C / 3750.3 Torr 2: 90 percent / H2 / 10percent Pd/C / ethanol / 48 h / 50 °C / 3750.3 Torr View Scheme