4-氨基丁酸乙酯.盐酸盐合成路线 （共 21 条）
反应条件
1: With sodium tris(acetoxy)borohydride 1.5 h; 2: With triethylamine T=20 - 60°C; 21 h; SolventTemperatureTime;
参考文献
Mapes, Christopher M.; Mani, Neelakandha S.
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 482 - 486
反应条件
hydrogenchloride; ammonium hydroxide 1.) 24 h, r.t., 2.) CH2Cl2; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Smith, Terence A.; Marshall, Jacqueline H. A.
Phytochemistry (Elsevier), 1988 , vol. 27, # 3 p. 703 - 710
反应条件
hydrogenchloride; ammonium hydroxide 1.) 24 h, r.t., 2.) CH2Cl2; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Smith, Terence A.; Marshall, Jacqueline H. A.
Phytochemistry (Elsevier), 1988 , vol. 27, # 3 p. 703 - 710
反应条件
triethylamine in dichloromethane; ethyl acetate
参考文献
E. R. Squibb and Sons, Inc.
Patent: US4555520 A1, 1985 ;
反应条件
(i) SOCl2, benzene, (ii) /BRN= 4304328/, (iii) /BRN= 3911780/, Et3N, dioxane; Multistep reaction;
参考文献
Martinez,A.P. et al.
Journal of Medicinal Chemistry, 1965 , vol. 8, p. 187 - 189
反应条件
triethylamine in dichloromethane
T=20°C; 24 h;
参考文献
Revotar Biopharmaceuticals AG
Patent: EP1577289 A1, 2005 ;
Location in patent: Page/Page column 21 ;
反应条件
sodium hydroxide in DMF (N,N-dimethyl-formamide); water
T=20°C;
参考文献
Ooyama, Yousuke; Matsugasako, Ai; Nagano, Tomoya; Oka, Kazuyuki; Kushimoto, Kohei; Komaguchi, Kenji; Imae, Ichiro; Harima, Yutaka
Journal of Photochemistry and Photobiology A: Chemistry, 2011 , vol. 222, # 1 p. 52 - 55
反应条件
hydrogenchloride; triethylamine in methanol; sodium hydroxide; dichloromethane; water
参考文献
Weidner, John J; Variano, Bruce F; Majuru, Shingai; Bhandarkar, Satej; Bay, William E; Sheilds, Lynn
Patent: US2004/48777 A1, 2004 ;
反应条件
(i) HCl, (ii) /BRN= 385737/; Multistep reaction;
参考文献
Thomae
Patent: DE2234399 , 1974 ;
Chem.Abstr., 1974 , vol. 80, # 108853
反应条件
(i) HCl, (ii) /BRN= 516726/; Multistep reaction;
参考文献
Thomae
Patent: DE2234399 , 1974 ;
Chem.Abstr., 1974 , vol. 80, # 108853
