1: 3-chloro-propionaldehyde diethyl acetal With lithium; 4,4'-di-tert-butylbiphenyl in tetrahydrofuran T=-78°C; 1 h; 2: With zinc dibromide in tetrahydrofuran T=-78 - 20°C; 3: 1-bromo-2-chloro-benzene With Pd(OAc)2(PPh3)2 in tetrahydrofuran T=70°C; Negishi cross-coupling reaction; 24 h; Further stages.;
参考文献
Yus, Miguel; Gomis, Joaquin
European Journal of Organic Chemistry, 2002 , # 12 p. 1989 - 1995
