4-氯-2,5-二甲氧基硝基苯合成路线 （共 10 条）
反应条件
1: With acetic acid; isopentyl nitrite T=20°C; Inert atmosphere; 2: With hydrogenchloride; copper(l) chloride in water T=0 - 80°C; Inert atmosphere;
参考文献
Watanabe, Kana; Iwata, Yusuke; Adachi, Satoshi; Nishikawa, Tomoyuki; Yoshida, Yuko; Kameda, Shunsuke; Ide, Mitsuaki; Saikawa, Yoko; Nakata, Masaya
Journal of Organic Chemistry, 2010 , vol. 75, # 16 p. 5573 - 5579
反应条件
nitric acid; silica gel in dichloromethane 0.583333 h; Ambient temperature;
参考文献
Tapia, Ricardo; Torres, Glenda; Valderrama, Jaime A.
Synthetic Communications, 1986 , vol. 16, # 6 p. 681 - 688
反应条件
2: acetic acid; aqueous nitric acid / unter Kuehlung View Scheme
参考文献
Helvetica Chimica Acta, , vol. 31, p. 525,535
参考文献
Helvetica Chimica Acta, , vol. 31, p. 525,535
反应条件
1: With FeCl3·6H2O; carbon in methanol T=65°C; 1 h; Inert atmosphere; 2: With hydrazine hydrate in methanol T=65°C; Inert atmosphere;
参考文献
Watanabe, Kana; Iwata, Yusuke; Adachi, Satoshi; Nishikawa, Tomoyuki; Yoshida, Yuko; Kameda, Shunsuke; Ide, Mitsuaki; Saikawa, Yoko; Nakata, Masaya
Journal of Organic Chemistry, 2010 , vol. 75, # 16 p. 5573 - 5579
反应条件
1: tin (II)-chloride 2: aqueous H2SO4; KI / 75 °C / Diazotization 3: copper-powder / 200 °C View Scheme
参考文献
Posternak et al.
Helvetica Chimica Acta, 1948 , vol. 31, p. 525,535
反应条件
1: methanol With sodium
2: 4-chloro-2,5-dimethoxy nitrobenzene in methanol
T=0°C; 48 h; Heating / reflux;
参考文献
Piotrowski, David W.; Rogers, Bruce N.; McWhorter JR., William W.; Walker, Daniel Patrick; Corbett, Jeffrey W.; Groppi JR., Vincent E.; Rudmann, Daniel G.
Patent: US2003/236287 A1, 2003 ;
Location in patent: Page 33, 34 ;
US 20030236287 A1
参考文献
Kalle and Co.
Patent: DE896591 , 1951 ;
反应条件
1: FeCl3*6H2O; NH2NH2; H2O / methanol / 1 h / 65 °C
2: pyridine / 24 h / 20 °C
View Scheme
参考文献
Tomatsu, Ayumi; Takemura, Syunji; Hashimoto, Kimiko; Nakata, Masaya
Synlett, 1999 , # 9 p. 1474 - 1476
反应条件
1: tin (II)-chloride
2: aqueous H2SO4; KI / 75 °C / Diazotization
View Scheme
参考文献
Posternak et al.
Helvetica Chimica Acta, 1948 , vol. 31, p. 525,535
