1-羟基环己烷丙酸 gamma-内酯合成路线 （共 73 条）
反应条件
pyridinium chlorochromate in dichloromethane
T=28°C; 1.5 h; celite;
参考文献
Baskaran, Sundarababu; Islam, Imadul; Chandrasekaran, Srinivasan
Journal of Organic Chemistry, 1990 , vol. 55, # 3 p. 891 - 895
反应条件
disodium hydrogenphosphate; sodium amalgam in methanol
T=-10°C; 0.5 h;
参考文献
Carretero, Juan Carlos; Lombaert, Stephane De; Ghosez, Leon
Tetrahedron Letters, 1987 , vol. 28, # 19 p. 2135 - 2138
反应条件
hydrogen; palladium dihydroxide in methanol
P=3800 Torr; 12 h; Ambient temperature;
参考文献
Aoyagi, Yutaka; Maeda, Mikiko; Moro, Akira; Kubota, Ken; Fujii, Yohko; Fukaya, Haruhiko; Ohta, Akihiro
Chemical and Pharmaceutical Bulletin, 1996 , vol. 44, # 10 p. 1812 - 1818
反应条件
cerium; iodine in tetrahydrofuran
2 h; Ambient temperature;
参考文献
Fukuzawa, Shin-ichi; Sumimoto, Norifumi; Fujinami, Tatsuo; Sakai, Shizuyoshi
Journal of Organic Chemistry, 1990 , vol. 55, # 5 p. 1628 - 1631
反应条件
cerium; iodine in tetrahydrofuran
2 h; Ambient temperature;
参考文献
Fukuzawa, Shin-ichi; Sumimoto, Norifumi; Fujinami, Tatsuo; Sakai, Shizuyoshi
Journal of Organic Chemistry, 1990 , vol. 55, # 5 p. 1628 - 1631
反应条件
(cetyl)Me3N(1+)MnO4(1-) in chloroform
T=50°C; 6 h;
参考文献
Rathore, Rajendra; Vankar, Padma S.; Chandrasekaran, S.
Tetrahedron Letters, 1986 , vol. 27, # 34 p. 4079 - 4082
反应条件
chloro-trimethyl-silane; tetraethylammonium p-toluenesulfonate in N,N-dimethyl-formamide
Ambient temperatureelectroreductive crossed hydrocoupling;
参考文献
Shono, Tatsuya; Ohmizu, Hiroshi; Kawakami, Souta; Sugiyama, Hiroshi
Tetrahedron Letters, 1980 , vol. 21, p. 5029 - 5032
反应条件
hydrogenchloride in ethanol
24 h; Heating;
参考文献
Katritzky, Alan R.; Feng, Daming; Lang, Hengyuan
Journal of Organic Chemistry, 1997 , vol. 62, # 12 p. 4131 - 4136
反应条件
1: With 4,4'-di-tert-butylbiphenyl; lithium in tetrahydrofuran
T=-78°C; Barbier-type reaction; 0.5 h;
2: With phosphate buffer
T=-78 - 20°C; pH=7; 0.25 h;
3: With toluene-4-sulfonic acid
T=20°C;
参考文献
Yus, Miguel; Torregrosa, Rosario; Pastor, Isidro M.
Molecules, 2004 , vol. 9, # 5 p. 330 - 348
反应条件
ammonium cerium(IV) nitrate in water; acetonitrile
1 h; Ambient temperature;
参考文献
Salomon, Robert G.; Roy, Subhas; Salomon, Mary F.
Tetrahedron Letters, 1988 , vol. 29, # 7 p. 769 - 772
