1: 2.) 0.5 N NaOH, air-O2 / 1.) THF, -40 deg, 2.) CH2Cl2, 5 min 2: 2.) 1N NaOH, air-O2 / 1.) CH2Cl2, room temp., 16 h, 2.) CH3OH, 5 min 3: 1.) 0.5 N NaOH, Na2S2O3, 2.) air / 1.) 60 deg C, 1 h, 2.) 10 min View Scheme

(i) THF, (ii) /BRN= 1743394/, toluene, (iii) HgO, H2SO4, acetone; Multistep reaction;