反应条件
1: sodium iodide / acetone / Ambient temperature
2: 1.) butyl-lithium, di-isopropylamine / 1.) hexane, THF, -78 deg C --> room temp., 10 min; 2.) THF, -78 deg C; -20 deg C, 5 d
3: 58 percent / LiAlH4 / tetrahydrofuran / 2 h / 0 °C / 2.) room temp., overnight
4: pyridine / room temp., overnight
5: lithium bromide / tetrahydrofuran / room temp., overnight
6: 30 percent / tetrahydrofuran; liquid ammonia
View Scheme
参考文献
Baker, Raymond; O'Mahony, Mary J.; Swain, Christopher J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 1623 - 1634
