1,3-二氮杂螺[4,5]癸烷-2,4-二酮合成路线 （共 35 条）
反应条件
1: CHCl3 / 3 h / 0 - 20 °C 2: 71 percent / tetrahydrofuran / 3 h / 0 - 20 °C 3: 85 percent / concd. HCl; glacial acetic acid / 5 h / Heating View Scheme
参考文献
Scientia Pharmaceutica, , vol. 69, # 4 p. 329 - 350
反应条件
in ethanol Bucherer-Lieb reaction; 6 h; Heating;
参考文献
Naydenova, Emilia; Pencheva, Nevena; Popova, Julita; Stoyanov, Neyko; Lazarova, Maria; Aleksiev, Boris
Farmaco, 2002 , vol. 57, # 3 p. 189 - 194
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 140, p. 129,135, 150
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 140, p. 151,167
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 140, p. 251,268
反应条件
1: 60 percent / barium hydroxide, water / 72 h / 160 °C 2: 61 percent / thionyl chloride / 12 h / Heating View Scheme
参考文献
Aboul-Enein, M. N.; El-Azzouny, A. A.; Abdallah, N. A.; Makhlouf, A. A.
Egyptian Journal of Chemistry, 1991 , vol. 34, # 6 p. 549 - 558
反应条件
1: beim aufeinanderfolgenden Erwaermen mit aethanol. Natriumaethylat und Chloressigsaeure-aethylester 2: aq. NaOH solution View Scheme
参考文献
Orazi; Corral
Anales de la Asociacion Quimica Argentina (1921-2001), 1954 , vol. 42, p. 177,181
参考文献
Orazi; Corral
Anales de la Asociacion Quimica Argentina (1921-2001), 1954 , vol. 42, p. 177,181
反应条件
potassium hydroxide in ethanol 16 h;
参考文献
Struck, Robert F.; Kirk, Marion C.; Rice, Louise S.; Suling, William J.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 7 p. 1319 - 1321
反应条件
Ba(OH)2·8H2O; water in water T=160°C; 2 h; Autoclave;
参考文献
Stoyanov, Neyko; Marinov, Marin
Acta Chimica Slovenica, 2012 , vol. 59, # 3 p. 680 - 685,6
Title/Abstract Full Text Show Details
Stoyanov, Neyko; Marinov, Marin
Acta Chimica Slovenica, 2012 , vol. 59, # 3 p. 680 - 685
参考文献
Gmelin Handbook: F: PerFHalOrg.1, 1.1.6.5.2, page 157 - 193
