5-氯-2-甲氧基苯甲醛合成路线 （共 12 条）
反应条件
1: 5-chloro-2-hydroxybenzaldehyde With sodium hydride in N,N-dimethyl-formamide; mineral oil T=0°C; 0.25 h; Inert atmosphere; 2: methyl iodide in N,N-dimethyl-formamide; mineral oil T=0 - 21°C; Inert atmosphere;
参考文献
Teichert, Johannes F.; Feringa, Ben L.
Chemical Communications, 2011 , vol. 47, # 9 p. 2679 - 2681
反应条件
Ca(OCl)2; acetic acid in water; acetonitrile Ambient temperature;
参考文献
Nwaukwa, Stephen O.; Keehn, Philip M.
Synthetic Communications, 1989 , vol. 19, # 5and6 p. 799 - 804
参考文献
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 221, p. 202
参考文献
Journal of the American Chemical Society, , vol. 73, p. 702
反应条件
sodium cyanoborohydride in methanol
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 3 p. 281 - 284
反应条件
3-chloro-benzenecarboperoxoic acid
参考文献
Burke Jr.; Jacobson; Rice; Silverton
Journal of Organic Chemistry, 1984 , vol. 49, # 6 p. 1051 - 1056
反应条件
hydrogenchloride; potassium hydroxide; hydrazine hydrate in tetrachloromethane; diethylene glycol
参考文献
Pfizer Inc.
Patent: US4617312 A1, 1986 ;
反应条件
sodium acetate; ammonium chloride in formic acid 4 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 12 p. 2251 - 2255
参考文献
Tang, Jing; Huang, Xian
Journal of Chemical Research - Part S, 2003 , # 6 p. 354 - 355
反应条件
(i) HC(OEt)3, H3PO4, (ii) /BRN= 605351/, ZnCl2, AcOEt, (iii) aq. NaOAc, AcOH; Multistep reaction;
参考文献
Billman; Tonnis
Journal of pharmaceutical sciences, 1971 , vol. 60, # 8 p. 1188 - 1192
