5-(3-吡啶基)-1,3-噁唑合成路线 (共 5 条)
反应条件
tetrakis(triphenylphosphine) palladium(0); water; sodium carbonate in 1,4-dioxane T=80°C; Suzuki cross-coupling; Inert atmosphere;
参考文献
Primas, Nicolas; Bouillon, Alexandre; Lancelot, Jean-Charles; Rault, Sylvain
Tetrahedron, 2009 , vol. 65, # 32 p. 6348 - 6353
反应条件
potassium tert-butylate in tetrahydrofuran; ethanol T=0°C; 2 h;
参考文献
Tetrahedron Letters, , vol. 30, # 48 p. 6657 - 6660
反应条件
potassium tert-butylate in tetrahydrofuran 2 h; Ambient temperature;
参考文献
Sasaki, Hideaki
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 8 p. 1369 - 1371
反应条件
potassium carbonate in methanol
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 27, # 3 p. 793 - 796
反应条件
1: 3-(oxazol-5-yl)pyridine With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.5 h; 2: (4-morpholinyl)methanone in tetrahydrofuran; hexane T=-78 - 20°C; 10 h;
参考文献
Merck and Co., Inc.
Patent: US6642237 B1, 2003 ;
Location in patent: Page/Page column 189 ;