4-[5-[[2-(氮杂环庚-1-基)-5-氰基-1-乙基-4-甲基-6-氧代-吡啶-3-基]亚甲基]-4-氧代-2-硫代-噻唑烷-3-基]丁酸合成路线 (共 24 条)
反应条件
n-butyllithium in tetrahydrofuran
参考文献
Yamamoto, Makoto; Suenaga, Tsuyoshi; Suzuki, Kzuya; Naruchi, Kiyoshi; Yamada, Kazutoshi
Heterocycles, 1987 , vol. 26, # 3 p. 755 - 758
参考文献
Zinner,G.; Guenther,H.
Angewandte Chemie, 1964 , vol. 76, p. 440
反应条件
hydroxide in water
T=25°C; buffer; diff. pH; diff. temp.; Rate constant;
参考文献
Egan, Carmel; Clery, Maurice; Hegarty, Anthony F.; Welch, Alan J.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1991 , # 2 p. 249 - 256
参考文献
Wieland, H.
Liebigs Annalen der Chemie, 1907 , vol. 353, p. 65 - 105
Show Details
Gmelin Handbook: Ag: MVol.B6, 1.17.3, page 320 - 320
反应条件
sulfuric acid in water
T=35°C; δH(excit.), ΔG(excit.), ΔS(excit.); further temperatures: 29-45 deg C; Product distributionThermodynamic dataRate constant;
参考文献
Yamuna, B.; Naidu, H. M. K.; Mahadevappa, D. S.
Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 1988 , vol. 27, # 7 p. 589 - 592
反应条件
in solid matrix
other Radiation; Matrix react. of O with CH3CN (solid argon, 15°C);
参考文献
Mielke, Zofia; Hawkins, Michael; Andrews, Lester
Journal of Physical Chemistry, 1989 , vol. 93, # 2 p. 558 - 564
参考文献
Pigou, Paul E.; Stirling, Charles J. M.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1988 , p. 725 - 730
反应条件
ozone
T=-258.2°C; Irradiationsolid Argon matrix; Product distributionMechanism;
参考文献
Mielke, Zofia; Hawkins, Michael; Andrews, Lester
Journal of Physical Chemistry, 1989 , vol. 93, # 2 p. 558 - 564
反应条件
in chloroform-d1
T=23°C;
参考文献
Mitchell, William R.; Paton, R. Michael
Arkivoc, 2010 , vol. 2010, # 10 p. 34 - 54
反应条件
in diethyl ether
T=-25°C;
参考文献
Cunico, Robert F.; Bedell, Louis
Journal of Organometallic Chemistry, 1985 , vol. 281, p. 135 - 140