(S)-2-溴-3-羟基丙酸合成路线 （共 3 条）
反应条件
1: With hydrogen bromide; potassium bromide in water
T=-15 - 30°C;
2: With sodium nitrite in water
T=-15 - 10°C; Inert atmosphere;
参考文献
INDOCO REMEDIES LIMITED; RAJADHYAKSHA, Mangesh, Narayan; NAIR, Ranjeet; SHRIGADI, Nilesh Balkrishna; PANANDIKAR Aditi Milind
Patent: WO2012/14226 A1, 2012 ;
Location in patent: Page/Page column 16 ;
反应条件
hydrogen bromide; sodium nitrite
ee = 90percent; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Larcheveque, Marc; Petit, Yves
Tetrahedron Letters, 1987 , vol. 28, # 18 p. 1993 - 1996
反应条件
hydrogen bromide; sodium nitrite
ee = 90percent; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Larcheveque, Marc; Petit, Yves
Tetrahedron Letters, 1987 , vol. 28, # 18 p. 1993 - 1996
