顺式-4-异丙基环己烷羧酸合成路线 （共 5 条）
反应条件
sodium hydroxide in methanol
0.166667 h; Ambient temperature;
参考文献
Shinkai; Nishikawa; Sato; Toi; Kumashiro; Seto; Fukama; Dan; Toyoshoma
Journal of Medicinal Chemistry, 1989 , vol. 32, # 7 p. 1436 - 1441
反应条件
1: 1) H2, 2) SOCl2 / 1) PtO2 / 1) 5 kg/cm2, r.t., 2 h
2: 64 percent / 2N aq. NaOH / methanol / 0.17 h / Ambient temperature
View Scheme
参考文献
Shinkai; Nishikawa; Sato; Toi; Kumashiro; Seto; Fukama; Dan; Toyoshoma
Journal of Medicinal Chemistry, 1989 , vol. 32, # 7 p. 1436 - 1441
反应条件
sodium hydroxide; nickel
T=195°C; P=73550.8 Torr; Hydrogenation;
参考文献
Cooke; Macbeth
Journal of the Chemical Society, 1939 , p. 1245
反应条件
sodium hydroxide; sodium hydride
1) 150 deg C, 2 h, 2) MeOH, 20 deg C, 10 min; Yield given. Multistep reaction;
参考文献
Shinkai; Nishikawa; Sato; Toi; Kumashiro; Seto; Fukama; Dan; Toyoshoma
Journal of Medicinal Chemistry, 1989 , vol. 32, # 7 p. 1436 - 1441
参考文献
Cooke; Macbeth; Swanson
Journal of the Chemical Society, 1940 , p. 808
