6-噁双环[3.1.0]-3-己烯合成路线 （共 22 条）
反应条件
1: 67 percent / <(i-C3H7O)3P>4Pd / tetrahydrofuran; dimethylsulfoxide / 1.) 0 deg C for 3 h 2.) 25 deg C overnight 2: osmium tetroxide, N-methyl-morpholine N-oxide View Scheme
参考文献
Journal of the American Chemical Society, , vol. 110, # 2 p. 621 - 622
反应条件
water; hydrogen; platinum(IV) oxide 1.) acetone, pH 8.0, 2.) ethanol, 12 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Ross, Angela M.; Pohl, Terese M.; Piazza, Kathryn; Thomas, Michael; Fox, Bonnie; Whalen, Dale L.
Journal of the American Chemical Society, 1982 , vol. 104, # 6 p. 1658 - 1665
反应条件
water; hydrogen; platinum(IV) oxide 1.) acetone, pH 8.0, 2.) ethanol, 12 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Ross, Angela M.; Pohl, Terese M.; Piazza, Kathryn; Thomas, Michael; Fox, Bonnie; Whalen, Dale L.
Journal of the American Chemical Society, 1982 , vol. 104, # 6 p. 1658 - 1665
反应条件
meta-chloroperoxybenzoic acid in chloroform overnight;
参考文献
Kozlov, N. S.; Yakubovich, L. S.; Zhavnerko, K. A.; Prishchepenko, V. M.
Journal of Organic Chemistry USSR (English Translation), 1982 , vol. 18, # 10 p. 1842 - 1846
Zhurnal Organicheskoi Khimii, 1982 , vol. 18, # 10 p. 2094 - 2099
反应条件
1: lithium aluminium tetrahydride / diethyl ether / 18 h / 0 °C 2: triethylamine / dichloromethane / 2 h / 0 °C View Scheme
参考文献
Scagnelli, Luca; Memeo, Misal Giuseppe; Carosso, Serena; Bovio, Bruna; Quadrelli, Paolo
European Journal of Organic Chemistry, 2013 , # 18 p. 3835 - 3846
反应条件
1: 70 percent / tetrahydrofuran / 1.5 h / -78 - 0 °C 2: 0.95 g / 30percent H2O2, 30 percent KOH / ethanol / 1.) 45 deg C, 1 h, 2.) reflux, 6 h 3: 91 percent / HCL / 0.67 h 4: 80 percent / pyridine / 1 h / 0 °C 5: 94 percent / 5percent NaOH / tetrahydrofuran / 24 h / 0 °C 6: 92 percent / conc. sulfuric acid / 1.) 80 deg C, 5 h, 2.) RT, 12 h 7: 6.2 g / sodium / methanol / 0.5 h / 0 °C View Scheme
参考文献
Miftakhov, M. S.; Adler, M. E.; Komissarova, N. G.; Tolstikov, G. A.
Journal of Organic Chemistry USSR (English Translation), 1990 , vol. 26, # 7.1 p. 1274 - 1280
Zhurnal Organicheskoi Khimii, 1990 , vol. 26, # 7 p. 1476 - 1484
反应条件
(i) (pyrolysis), (ii) /BRN= 1098229/; Multistep reaction;
参考文献
Schiess,P.; Radimerski,P.
Helvetica Chimica Acta, 1974 , vol. 57, # 283 p. 2583 - 2597
反应条件
tetrakis(triphenylphosphine) palladium(0); triglyme (triethylene glycol dimethyl ether) in tetrahydrofuran T=0°C; 1 h; Schlenk techniqueInert atmosphere; Reagent/catalystSolvent; Overall yield = 85 percentChromat.;
参考文献
Hamasaki, Akiyuki; Maruta, Shuhei; Nakamura, Aki; Tokunaga, Makoto
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 11-12 p. 2129 - 2134
反应条件
tetrakis(triphenylphosphine) palladium(0); triglyme (triethylene glycol dimethyl ether) in tetrahydrofuran T=0°C; 1 h; Schlenk techniqueInert atmosphere; Reagent/catalystSolvent; Overall yield = 85 percentChromat.;
参考文献
Advanced Synthesis and Catalysis, , vol. 354, # 11-12 p. 2129 - 2134
反应条件
sodium perchlorate; water in acetone T=25°C; pH - rate profile; Rate constantMechanism;
参考文献
Journal of the American Chemical Society, , vol. 104, # 6 p. 1658 - 1665
