1-苄基嘧啶-2,4-二酮合成路线 （共 26 条）
参考文献
Sako, Magoichi; Hirota, Kosaku; Maki, Yoshifumi
Tetrahedron, 1983 , vol. 39, # 23 p. 3919 - 3922
反应条件
1: 32 percent / POCl3 / H2O / 2 h / Heating
2: 71 percent / 25percent aq. NH3, Zn / ethanol / 4 h / 90 °C
View Scheme
参考文献
Nagamatsu, Tomohisa; Yamasaki, Hirofumi; Yoneda, Fumio
Heterocycles, 1994 , vol. 37, # 2 p. 1147 - 1164
反应条件
1: 70 percent / 40 °C
2: 66 percent / HCl / H2O; dioxane / 1 h / Heating
View Scheme
参考文献
Maruyama, Tokumi; Kozai, Shigetada; Uchida, Mayuko
Nucleosides and Nucleotides, 1999 , vol. 18, # 4-5 p. 661 - 671
反应条件
1: diethyl ether; dichloromethane / 18 h / 0 °C
2: tetrabutyl ammonium fluoride; tris-(dibenzylideneacetone)dipalladium(0); thiophene / tetrahydrofuran; N,N-dimethyl-formamide; water / 1 h / 100 °C / |Inert atmosphere
View Scheme
参考文献
Liang, Yong; Gloudeman, Jennifer; Wnuk, Stanislaw F.
Journal of Organic Chemistry, 2014 , vol. 79, # 9 p. 4094 - 4103
反应条件
tris-(dibenzylideneacetone)dipalladium(0) in tetrahydrofuran; water; N,N-dimethyl-formamide
T=100°C; 6 h; Inert atmosphere;
参考文献
Liang, Yong; Gloudeman, Jennifer; Wnuk, Stanislaw F.
Journal of Organic Chemistry, 2014 , vol. 79, # 9 p. 4094 - 4103
反应条件
potassium carbonate
1.) DMF, room temp., overnight 2.) DMF, room temp., 2 days; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Kundu, Nitya G.; Sikdar, Sikha; Hertzberg, Robert P.; Schmitz, Scott A.; Khatri, Surenda G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1295 - 1300
