2-氨基-5-氯二苯甲酮合成路线 （共 174 条）
反应条件
1: 5 mol/l HCl / Ambient temperature 2: 5 M HCl / Heating; hydrolysis View Scheme
参考文献
Pharmazie, , vol. 42, # 1 p. 54 - 55
反应条件
1.1: tert.-butyl lithium / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere 1.2: 1.25 h / -40 °C / Inert atmosphere 2.1: hydrogenchloride; water / ethanol / Reflux 2.2: pH 8 View Scheme
参考文献
Molecules, , vol. 16, # 9 p. 7649 - 7661
反应条件
1.1: N-ethyl-N,N-diisopropylamine / toluene / 20 °C 2.1: tert.-butyl lithium / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere 2.2: 1.25 h / -40 °C / Inert atmosphere 3.1: hydrogenchloride; water / ethanol / Reflux 3.2: pH 8 View Scheme
参考文献
Molecules, , vol. 16, # 9 p. 7649 - 7661
反应条件
hydrogenchloride 10 h;
参考文献
Schleuder, M.; Butzki, Susanne; Richter, P.; Sokolov, A.
Pharmazie, 1987 , vol. 42, # 1 p. 54 - 55
反应条件
in ethanol T=60°C; 3 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 29, # 8 p. 2135 - 2156
反应条件
potassium hydroxide in ethanol Heating;
参考文献
Pharmazie, , vol. 45, # 12 p. 933 - 934
反应条件
potassium hydroxide in ethanol Heating;
参考文献
Pharmazie, , vol. 45, # 12 p. 933 - 934
反应条件
PPA T=85 - 90°C; 18 h; Yield given. Yields of byproduct given;
参考文献
Journal of Heterocyclic Chemistry, , vol. 26, p. 1611 - 1618
反应条件
1: 85 percent / Cl2 / acetic acid / 1 h / 80 °C 2: 31 percent / AlCl3 / 5 h / Heating View Scheme
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 43, # 12 p. 2689 - 2695
反应条件
1: KOH / ethanol / Heating 2: KOH / ethanol / Heating View Scheme
参考文献
Pharmazie, , vol. 45, # 12 p. 933 - 934
