2-氨基-5-氯二苯甲酮合成路线 （共 174 条）
反应条件
hydrogenchloride in methanol; water T=50°C; 360 h; Product distribution;
参考文献
Journal of Pharmaceutical Sciences, , vol. 84, # 2 p. 208 - 211
反应条件
aluminium trichloride 1) ethylene chloride, 1 h 2) ethylene chloride, MeOH, 45 min; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 26, # 1-12 p. 1133 - 1139
反应条件
hydrogenchloride 10 h; Heating;
参考文献
Schleuder; Butzki; Richter
Pharmazie, 1984 , vol. 39, # 7 p. 505 - 506
反应条件
aluminium trichloride 1) ethylene chloride, 1 h 2) ethylene chloride, 45 min; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 26, # 1-12 p. 1133 - 1139
反应条件
aluminium trichloride 1) ethylene chloride, 1 h 2) ethylene chloride, 45 min; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 26, # 1-12 p. 1133 - 1139
反应条件
hydrogenchloride in water 5 h; Heatinghydrolysis, further solvent and reagent;
参考文献
Bahr; Dietz
Pharmazie, 1980 , vol. 35, # 5-6 p. 256 - 263
反应条件
hydrogen in dimethylsulfoxide-d6 96 h; variation of pH, ionic strength, temperatute; δH excit, ΔE excit, ΔS excit, ΔG excit; MechanismThermodynamic data;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 32, # 3 p. 1080 - 1090
反应条件
hydrogenchloride in water Ambient temperatureinfluence of pH: maximum stability at pH 5.5-6.5; acceleration of the hydrolysis by day light; Rate constant;
参考文献
Pharmazie, , vol. 48, # 1 p. 33 - 37
反应条件
hydrogenchloride 0.5 h; Heatingreflux;
参考文献
Schleuder, M.; Butzki, Susanne; Richter, P.; Sokolov, A.
Pharmazie, 1987 , vol. 42, # 1 p. 54 - 55
反应条件
hydrogenchloride multistep reaction: biotransformation, acid hydrolysis;
参考文献
Arzneimittel-Forschung/Drug Research, , vol. 32, # 3 p. 177 - 183
