2,2-二甲基-己-4-炔-3-酮合成路线 （共 8 条）
反应条件
aluminium trichloride in dichloromethane
T=15°C; 2.5 h;
参考文献
Saba, Shahrokh; Wolff, Steven; Schroeder, Clemens; Margaretha, Paul; Agosta, William C.
Journal of the American Chemical Society, 1983 , vol. 105, # 23 p. 6902 - 6907
反应条件
1: in diethyl ether; hexane; pentane
T=-78°C; Inert atmosphere;
2: With titanium tetrachloride in dichloromethane
T=-78 - 20°C; Diels-Alder reaction; Molecular sieve;
参考文献
Yadav; Bhasker, E. Vijaya; Srihari
Tetrahedron, 2010 , vol. 66, # 11 p. 1997 - 2004
反应条件
in tetrahydrofuran
T=0°C; 0.5 h;
参考文献
De Las Heras, Maria A.; Vaquero, Juan J.; Garcia Navio, Jose L.; Alvarez-Builla, Julio
Tetrahedron, 1996 , vol. 52, # 45 p. 14297 - 14310
反应条件
in diethyl ether; hexane; pentane
T=-78°C; Inert atmosphere;
参考文献
Yadav; Bhasker, E. Vijaya; Srihari
Tetrahedron, 2010 , vol. 66, # 11 p. 1997 - 2004
反应条件
1: in diethyl ether; hexane; pentane
T=-78°C; Inert atmosphere;
2: With titanium tetrachloride in dichloromethane
T=-78 - 20°C; Diels-Alder reaction; Molecular sieve;
参考文献
Yadav; Bhasker, E. Vijaya; Srihari
Tetrahedron, 2010 , vol. 66, # 11 p. 1997 - 2004
反应条件
dipyridinium dichromate; 3 A molecular sieve in dichloromethane
参考文献
Corey, E. J.; Boaz, Neil W.
Tetrahedron Letters, 1984 , vol. 25, # 29 p. 3055 - 3058
反应条件
1: 75 percent / 5-methyl-2-chloro-3-phenyl-2,3-dihydro-1,3,4,2-oxadiazaphosphole, pyridine / Ambient temperature
2: 70 percent / tetrahydrofuran / 0.5 h / 0 °C
View Scheme
参考文献
De Las Heras, Maria A.; Vaquero, Juan J.; Garcia Navio, Jose L.; Alvarez-Builla, Julio
Tetrahedron, 1996 , vol. 52, # 45 p. 14297 - 14310
反应条件
1: 1.) n-butyllithium / 1.) THF, 2.) THF, 0 deg C
2: pyridinium dichromate (PDC), 3 Angstroem molecular sieve / CH2Cl2
View Scheme
参考文献
Corey, E. J.; Boaz, Neil W.
Tetrahedron Letters, 1984 , vol. 25, # 29 p. 3055 - 3058
