1: H-L-Lol-2-chlorotrityl resin; fmoc-L-Ile-OH With N-ethyl-N,N-diisopropylamine; HATU 1 h; solid phase reaction; 2: With piperidine in N,N-dimethyl-formamide solid phase reaction; 3: octanoic acid; N-(9-fluorenylmethoxycarbonyl)glycine; N-Fmoc-L-leucine; Fmoc-(α-aminoisobutyric acid)

1: C29H30NO7Pol With piperidine in N,N-dimethyl-formamide 0.333333 h; solid phase reaction; 2: N-(fluoren-9-ylmethoxycarbonyl)-L-Lys(Nε-Boc) With 4-methyl-morpholine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate in dichloromethane; N,N-dimethyl-formamide 2 h; solid phase reaction; 3: N-(9-fluorenylmethoxycarbonyl)glycine; N-Fmoc-L-leucine; Fmoc–Pro–OH; Fmoc-L-phenylalanine; fmoc-L-Ile-OH; fmoc-O-tert-butyl-L-tyrosine; fmoc-L-Arg(Pbf)-OH Further stages;

1: fmoc-L-Ile-OH With N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 0.5 h; 2: With N-ethyl-N,N-diisopropylamine in methanol; dichloromethane 3: fmoc-L-Ile-OH Further stages;