(E)-2-丁烯基乙酸酯合成路线 （共 41 条）
反应条件
(-)-2,3-O-isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphanyl)butane; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
6 h; Ambient temperature; Yields of byproduct given;
参考文献
Hiroi, Kunio; Makino, Kunitaka
Chemistry Letters, 1986 , p. 617 - 620
反应条件
copper; Cu(II) perchlorate in tetrahydrofuran
6 h; Heating; Yield given;
参考文献
Baruah, Jubaraj B.; Samuelson, Ashoka G.
Journal of Organometallic Chemistry, 1989 , vol. 361, p. C57 - C60
反应条件
[Ni0(1,5-cyclooctadiene)2]; tri-cyclo-hexyl-phosphine in ethyl acetate
T=60°C; 12 h; Inert atmosphere; stereoselective reaction;
参考文献
Zhang, Ping; Roundtree, Ian A.; Morken, James P.
Organic Letters, 2012 , vol. 14, # 6 p. 1416 - 1419
反应条件
[(PPh3)3Pd] in N,N-dimethyl-formamide
T=120°C; 5 h;
参考文献
Inoue, Yoshio; Taguchi, Masaaki; Toyofuku, Masanori; Hashimoto, Harukichi
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 10 p. 3021 - 3022
反应条件
1: (E)-crotyl acetate With indium(III) chloride; dimethyl(n-butyl)amine; lithium chloride; indium; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide
T=35°C;
2: monoiodonaphthalene in N,N-dimethyl-formamide
T=100°C; Title compound not separated from byproducts;
参考文献
Lee, Phil Ho; Seomoon, Dong; Lee, Kooyeon; Kim, Sundae; Kim, Hyunseok; Kim, Hyun; Shim, Eunkyong; Lee, Miae; Lee, Seokju; Kim, Misook; Sridhar, Madabhushi
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 13-15 p. 1641 - 1645
反应条件
dimethyl amine; diiron nonacarbonyl in N,N-dimethyl-formamide
T=20°C; Title compound not separated from byproducts.;
参考文献
Akermark, Bjoern; Sjoegren, Magnus P. T.
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 17-18 p. 2641 - 2646
反应条件
1: methyl malonic acid diethylester With sodium hydride in tetrahydrofuran
T=0°C;
2: (E)-crotyl acetate With substituted-biphenyl-phosphoramideite; [(η3-allyl)Pd(OAc)]2 in tetrahydrofuran
T=20°C; 2 h; Title compound not separated from byproducts;
参考文献
Boele, Maarten D. K.; Kamer, Paul C. J.; Lutz, Martin; Spek, Anthony L.; De Vries, Johannes G.; Van Leeuwen, Piet W. N. M.; Van Strijdonck, Gino P. F.
Chemistry - A European Journal, 2004 , vol. 10, # 24 p. 6232 - 6246
反应条件
1: methyl malonic acid diethylester With sodium hydride in tetrahydrofuran
T=-0.16°C; deprotonation;
2: (E)-crotyl acetate With [Pd(C4H7){o-C5H4N(CH2)2OPPh2}][O3SCF3] in tetrahydrofuran
T=18.84°C; Alkylation; 24 h; Further stages. Title compound not separated from byproducts.;
参考文献
Van Haaren, Richard J.; Druijven, Cees J. M.; Van Strijdonck, Gino P. F.; Oevering, Henk; Reek, Joost N. H.; Kamer, Paul C. J.; Van Leeuwen, Piet W. N. M.
Journal of the Chemical Society, Dalton Transactions, 2000 , # 10 p. 1549 - 1554
反应条件
2,9-dimethyl-1,10-phenanthroline; lt;Pd(dmphen)(η3-allyl)gt; in N,N-dimethyl-formamide
T=20°C; 1 h; also Z isomer; Product distribution;
参考文献
Akermark, Bjoern; Hansson, Sverker; Vitagliano, Aldo
Journal of the American Chemical Society, 1990 , vol. 112, # 11 p. 4587 - 4588
反应条件
(crotyl)Pd(dppe) in tetrahydrofuran
T=18.85°C; Product distribution; Further Variations:Catalysts;
参考文献
Van Haaren, Richard J.; Oevering, Henk; Coussens, Betty B.; Van Strijdonck, Gino P. F.; Reek, Joost N. H.; Kamer, Paul C. J.; Van Leeuwen, Piet W. N. M.
European Journal of Inorganic Chemistry, 1999 , # 8 p. 1237 - 1241
