二氢-4-丙基-2(3H)-呋喃酮合成路线 （共 5 条）
反应条件
hydrogen; palladium on activated charcoal in acetic acid
T=30°C; P=22501.8 Torr; 16 h;
参考文献
Roeder, Erhard; Krauss, Hiltrud
Liebigs Annalen der Chemie, 1992 , # 3 p. 177 - 182
反应条件
1: With benzophenone
16 h; Irradiation;
2: With bromine; barium carbonate in 1,4-dioxane; water
T=20°C; 2 h;
参考文献
Dondi, Daniele; Caprioli, Ilaria; Fagnoni, Maurizio; Mella, Mariella; Albini, Angelo
Tetrahedron, 2003 , vol. 59, # 7 p. 947 - 957
反应条件
1: n-propyl-magnesium bromide With copper(l) iodide in diethyl ether
T=-20°C; 0.5 h;
2: 2,5-dihydro-2-furanone With chloro-trimethyl-silane in diethyl ether
T=-40 - 20°C;
3: With ammonium chloride in diethyl ether
T=20°C;
参考文献
Kenda, Benoit M.; Matagne, Alain C.; Talaga, Patrice E.; Pasau, Patrick M.; Differding, Edmond; Lallemand, Benedicte I.; Frycia, Anne M.; Moureau, Florence G.; Klitgaard, Henrik V.; Gillard, Michel R.; Fuks, Bruno; Michel, Philippe
Journal of Medicinal Chemistry, 2004 , vol. 47, # 3 p. 530 - 549
反应条件
tri(2-furyl)germane in water
T=25°C; 5 h;
参考文献
Nakamura; Yorimitsu; Shinokubo; Oshima
Bulletin of the Chemical Society of Japan, 2001 , vol. 74, # 4 p. 747 - 752
反应条件
1: 36 percent / NaAlH2Et2 / toluene; diethyl ether / 16 h / Ambient temperature
2: 63 percent / H2 / 10percent Pd/C / acetic acid / 16 h / 30 °C / 22501.8 Torr
View Scheme
参考文献
Roeder, Erhard; Krauss, Hiltrud
Liebigs Annalen der Chemie, 1992 , # 3 p. 177 - 182
