反应条件
1: phosphonic acid diethyl ester With lithium hexamethyldisilazane in tetrahydrofuran
T=-10°C; 0.333333 h; Inert atmosphere;
2: 3-methyl-1,2,4-oxadiazol-5-ylmethyl chloride in tetrahydrofuran
T=-10 - 20°C;
参考文献
RECORDATI IRELAND LIMITED; LEONARDI, Amedeo; MOTTA, Gianni; RIVA, Carlo; GUARNERI, Luciano; GRAZIANI, Davide; MARINONI, Fabio; BETTINELLI, Ilaria
Patent: WO2011/29633 A1, 2011 ;
Location in patent: Page/Page column 62 ;
WO 2011/029633 A1
