3-氯-2-氟-5-(三氟甲基)吡啶合成路线 （共 16 条）
反应条件
tetrabutylammomium bromide in water
参考文献
DowElanco
Patent: US5049675 A1, 1991 ;
反应条件
indium; [N-butylthiazolium][Br] T=95°C; 14 h; Green chemistry;
参考文献
Molecules, , vol. 18, # 1 p. 398 - 407
反应条件
1: 3-chloro-2-fluoro-5-(trifluoro-methyl)pyridine; (R)-(+)-2-(4-hydroxyphenoxy)propionic acid With potassium phosphate; tetra-(n-butyl)ammonium iodide in N,N-dimethyl-formamide T=50 - 60°C; 2 h; 2: With 2,4,6-trichloro-1,3,5-triazine in N,N-dimethyl-formamide T=5 - 25°C; 1.16667 h; 3: methanol in N,N-dimethyl-formamide
参考文献
Kalhor, Mehdi; Dadras, Akbar; Mobinikhaledi, Akbar; Tajik, Hassan
Journal of the Chilean Chemical Society, 2011 , vol. 56, # 4 p. 833 - 836
反应条件
FeCl3 in (2S)-N-methyl-1-phenylpropan-2-amine hydrate
参考文献
The Dow Chemical Company
Patent: US4546192 A1, 1985 ;
参考文献
The Dow Chemical Company
Patent: US4546192 A1, 1985 ;
反应条件
[Pd(P{(C6H11)3})2]; potassium acetate in 1,4-dioxane T=100°C; 0.833333 h;
参考文献
Tan, John Q.; Kim, Ronald M.; Mirc, John W.
Patent: US2013/210798 A1, 2013 ;
Location in patent: Paragraph 0207; 0208 ;
