4’-甲氧基[1,1’-联苯]-4-甲酸甲酯合成路线 （共 70 条）
反应条件
[Ni0(1,5-cyclooctadiene)2]; potassium phosphate; tri-cyclo-hexyl-phosphine in water; tert-butyl alcohol T=40°C; Suzuki-Miyaura cross-coupling; 2 h; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 77, # 14 p. 5956 - 5964
反应条件
potassium phosphate; [NiCl(1-naph)(PPh3)2]; tri-cyclo-hexyl-phosphine in tetrahydrofuran T=20°C; Suzuki-Miyaura cross-coupling; 3 h; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 77, # 14 p. 5956 - 5964
反应条件
[Ni0(1,5-cyclooctadiene)2]; potassium phosphate; tri-cyclo-hexyl-phosphine in dimethyl sulfoxide T=23°C; Suzuki-Miyaura cross-coupling; 3 h; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 77, # 14 p. 5956 - 5964
反应条件
pyridine; NiI2; 4,4'-dimethyl-2,2'-bipyridine; N,N-dimethyl acetamide; tetra-(n-butyl)ammonium iodide; magnesium chloride; zinc T=25°C; 12 h; Inert atmosphereSchlenk techniqueGlovebox;
参考文献
Qian, Qun; Zang, Zhenhua; Wang, Shulin; Chen, Yang; Lin, Kunhua; Gong, Hegui
Synlett, 2013 , vol. 24, # 5 art. no. ST-2012-W1102-L, p. 619 - 624
反应条件
1: AlCl3 / CS2 2: KMnO4, aq. NaOH 3: (esterification) View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 33, p. 5 - 7
反应条件
potassium carbonate in acetonitrile 6 h; Heating;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 16, # 7 p. 3732 - 3743
反应条件
1: potassium phosphate / tetrahydrofuran 2: potassium phosphate; [Ni0(1,5-cyclooctadiene)2]; tri-cyclo-hexyl-phosphine / tetrahydrofuran / 20 °C / Inert atmosphere View Scheme
参考文献
Journal of Organic Chemistry, , vol. 77, # 14 p. 5956 - 5964
反应条件
palladium; triphenylphosphine in tetrahydrofuran T=70°C; Negishi Coupling; 48 h; Inert atmosphereGreen chemistry; Catalytic behavior;
参考文献
Wu, Wei-Yi; Lin, Tze-Chiao; Takahashi, Tamotsu; Tsai, Fu-Yu; Mou, Chung-Yuan
ChemCatChem, 2013 , vol. 5, # 4 p. 1011 - 1019
反应条件
sodium methylate; caesium carbonate; potassium iodide; Merrifield resin; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride 1.) DMF, 80 deg C, 18 h; 2.) THF, r.t., 18 h; 3.) THF, 70 deg C, 18 h; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 37, # 31 p. 5491 - 5494
反应条件
1: pyridine / dichloromethane / 4 h / 0 - 20 °C / Inert atmosphere 2: bis(1,5-cyclooctadiene)nickel (0); cesium fluoride; tri-cyclo-hexyl-phosphine / toluene / 24 h / 120 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 77, # 2 p. 1018 - 1025
