反应条件
1: 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl-4',4',5',5'-tetramethyl-1,3,2-dioxaborolane With dimethyl zinc; Mg(O-t-Bu)2 in 1,4-dioxane; hexane T=0 - 20°C; 0.5 h; Schlenk techniqueGloveboxInert atmosphere; 2: 1-bromo-4-fluoro-2-iodobenzene in 1,4-dioxane; hexane T=20 - 120°C; 24 h; Schlenk techniqueGloveboxInert atmosphere; 3: With water in 1,4-dioxane; hexane T=20°C; 0.0833333 h; Schlenk techniqueGloveboxInert atmosphere; Overall yield = 83 percent; regioselective reaction;
参考文献
Nagashima, Yuki; Takita, Ryo; Yoshida, Kengo; Hirano, Keiichi; Uchiyama, Masanobu
Journal of the American Chemical Society, 2013 , vol. 135, # 50 p. 18730 - 18733
