N-3-[3-(1-哌啶甲基)-苯氧基]丙胺合成路线 （共 18 条）
反应条件
sodium chloride in sodium hydroxide; dimethyl sulfoxide; benzene
参考文献
Snow Brand Milk Products Co., Ltd.
Patent: US5317026 A1, 1994 ;
反应条件
sodium hydroxide in N,N-dimethyl-formamide T=85 - 90°C; 2 h;
参考文献
Tarpanov, Velichko; Vlahov, Radoslav; Penkov, Miho; Krikorian, Dikran; Parushev, Stoyan; Mechkarova, Pepa; Angelova, Nely; Schunack, Walter
Synthetic Communications, 1999 , vol. 29, # 1 p. 15 - 20
反应条件
1: 77.2 percent / HCOOH / 2 h / 110 °C 2: 92.5 percent / NaOH / dimethylformamide / 2 h / 85 - 90 °C View Scheme
参考文献
Synthetic Communications, , vol. 29, # 1 p. 15 - 20
反应条件
1: 77.2 percent / HCOOH / 2 h / 110 °C 2: 92.5 percent / NaOH / dimethylformamide / 2 h / 85 - 90 °C View Scheme
参考文献
Synthetic Communications, , vol. 29, # 1 p. 15 - 20
反应条件
1: piperidine; meta-hydroxybenzaldehyde With formic acid 2: acrylonitrile 3: With lithium aluminium tetrahydride in diethyl ether
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 10 p. 1717 - 1720
反应条件
1: 79 percent / 1.) 40 percent benzyltrimethylammonium hydroxide/MeOH, 2.) gaseous HCl / diethyl ether; propan-2-ol / 24 h / Heating 2: 60 percent / LiAlH4 / diethyl ether / 0.5 h / Ambient temperature View Scheme
参考文献
Arzneimittel-Forschung/Drug Research, , vol. 35, # 7 p. 1025 - 1029
反应条件
lithium aluminium tetrahydride
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 15 p. 3886 - 3890
反应条件
in butan-1-ol 3 h; Heating;
参考文献
Ogawa; Yoshida; Aratani; Koshinaka; Kato; Ito
Chemical and pharmaceutical bulletin, 1988 , vol. 36, # 8 p. 2955 - 2967
反应条件
N,O-bis-(trimethylsilyl)-acetamide in dichloromethane 0.5 h; Ambient temperature;
参考文献
Ueda; Ishii; Shinozaki; Seiki; Arai; Hatanaka
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 11 p. 3035 - 3041
反应条件
1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane 12 h; Ambient temperature;
参考文献
Sekine, Yasuo; Hirakawa, Nobuhiko; Kashiwaba, Noriaki; Matsumoto, Hajime; Kutsuma, Teruo; Yamaura, Tetsuaki; Sekine, Akihiro
Chemical and Pharmaceutical Bulletin, 1998 , vol. 46, # 4 p. 610 - 615
