二氢-5-壬基-2(3H)-呋喃酮合成路线 （共 10 条）
反应条件
sulfuric acid in water
T=100°C; 48 h;
参考文献
Patel, Nandini C.; Schwarz, Jacob B.; Islam, Khondaker; Miller, Whitney; Tran, Tuan P.; Wei, Yunjing
Synthetic Communications, 2011 , vol. 41, # 15 p. 2209 - 2215
反应条件
pyridinium chlorochromate in dichloromethane
T=20 - 25°C; Yield given. Yields of byproduct given;
参考文献
Sorochinskaya, A. M.; Kovalev, B. G.; Avdeeva, L. A.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 2 p. 277 - 283
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 2 p. 316 - 323
反应条件
T=110 - 145°C; 0.5 h;
参考文献
Sorochinskaya, A. M.; Kovalev, B. G.; Avdeeva, L. A.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 2 p. 277 - 283
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 2 p. 316 - 323
反应条件
1: 1) Mg, ether / 1) 2 h, <10 deg C 2) 36-38 deg C, 4 h
2: 62 percent / HCl / 2.5 h / Heating
3: 86.4 percent / LiAlH4 / diethyl ether / 5 h / Ambient temperature
4: pyridinium chlorochromate / CH2Cl2 / 20 - 25 °C
View Scheme
参考文献
Sorochinskaya, A. M.; Kovalev, B. G.; Avdeeva, L. A.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 2 p. 277 - 283
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 2 p. 316 - 323
反应条件
1: 62 percent / HCl / 2.5 h / Heating
2: 86.4 percent / LiAlH4 / diethyl ether / 5 h / Ambient temperature
3: pyridinium chlorochromate / CH2Cl2 / 20 - 25 °C
View Scheme
参考文献
Sorochinskaya, A. M.; Kovalev, B. G.; Avdeeva, L. A.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 2 p. 277 - 283
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 2 p. 316 - 323
反应条件
1: 1) Mg, ether / 1) 2 h, <10 deg C 2) 36-38 deg C, 4 h
2: 62 percent / HCl / 2.5 h / Heating
3: 86.4 percent / LiAlH4 / diethyl ether / 5 h / Ambient temperature
4: pyridinium chlorochromate / CH2Cl2 / 20 - 25 °C
View Scheme
参考文献
Sorochinskaya, A. M.; Kovalev, B. G.; Avdeeva, L. A.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 2 p. 277 - 283
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 2 p. 316 - 323
反应条件
1: 86.4 percent / LiAlH4 / diethyl ether / 5 h / Ambient temperature
2: pyridinium chlorochromate / CH2Cl2 / 20 - 25 °C
View Scheme
参考文献
Sorochinskaya, A. M.; Kovalev, B. G.; Avdeeva, L. A.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 2 p. 277 - 283
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 2 p. 316 - 323
反应条件
1: 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 16 h / 20 °C
2: sulfuric acid / water / 48 h / 100 °C
View Scheme
参考文献
Patel, Nandini C.; Schwarz, Jacob B.; Islam, Khondaker; Miller, Whitney; Tran, Tuan P.; Wei, Yunjing
Synthetic Communications, 2011 , vol. 41, # 15 p. 2209 - 2215
反应条件
1: piperidine; acetic acid / 0.42 h / 0 - 20 °C
2: 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 16 h / 20 °C
3: sulfuric acid / water / 48 h / 100 °C
View Scheme
参考文献
Patel, Nandini C.; Schwarz, Jacob B.; Islam, Khondaker; Miller, Whitney; Tran, Tuan P.; Wei, Yunjing
Synthetic Communications, 2011 , vol. 41, # 15 p. 2209 - 2215
反应条件
Hydrolysis.Decarboxylierung;
参考文献
Rothstein
Bulletin de la Societe Chimique de France, 1935 , vol. <5>2, p. 1939
