1: 5-bromo-pyrimidin-2-ylamine With sodium hydride in N,N-dimethyl-formamide; mineral oil T=0°C; 0.25 h; 2: methyl iodide in N,N-dimethyl-formamide; mineral oil T=0 - 20°C; 4.5 h;
Lee, S. Y. Tina; Ghani, Amylia Abdul; D'Elia, Valerio; Cokoja, Mirza; Herrmann, Wolfgang A.; Basset, Jean-Marie; Kuehn, Fritz E.
New Journal of Chemistry, 2013 , vol. 37, # 11 p. 3512 - 3517
1: β-cyclodextrin With sodium hydride in dimethyl sulfoxide T=20°C; 1 h; Inert atmosphere; 2: methyl iodide in dimethyl sulfoxide T=0°C; Inert atmosphere;
参考文献
Zhou, You; Lindbaeck, Emil; Marinescu, Lavinia G.; Pedersen, Christian Marcus; Bols, Mikael
European Journal of Organic Chemistry, 2012 , # 21 p. 4063 - 4070