1,1-环戊烷二羧酸二甲酯合成路线 （共 11 条）
反应条件
potassium carbonate; [bbim]BF4 in N,N-dimethyl-formamide
T=20°C; 6 h;
参考文献
Muthusamy, Sengodagounder; Gnanaprakasam, Boopathy
Tetrahedron Letters, 2005 , vol. 46, # 4 p. 635 - 638
反应条件
L-Selectridereg; in tetrahydrofuran
T=0°C;
参考文献
Little, R. Daniel; Verhe, Roland; Monte, William T.; Nugent, Sean; Dawson, James R.
Journal of Organic Chemistry, 1982 , vol. 47, # 2 p. 362 - 364
反应条件
n-butyllithium; diisopropylamine in tetrahydrofuran; hexane
T=-78°C;
参考文献
Davis, Charles R.; Swenson, Dale C.; Burton, Donald J.
Journal of Organic Chemistry, 1993 , vol. 58, # 24 p. 6843 - 6850
反应条件
potassium carbonate in N,N-dimethyl-formamide
1.) 25 deg C, 24 h, 2.) from 25 deg C to 100 deg C, 2 h;
参考文献
Newkome, George R.; Baker, Gregory R.; Arai, Sadao; Saunders, Mary Jane; Russo, Paul S.; Theriot, Kevin J.; Moorefield, Charles N.; Rogers, L. Edward; Miller, Joseph E.; Lieux, T. Richard; Murray, Mary E.; Phillips, Buffie; Pascal, Laura
Journal of the American Chemical Society, 1990 , vol. 112, # 23 p. 8458 - 8465
反应条件
N(Et)4ClO4 in N,N-dimethyl-formamide
electrolysis;
参考文献
Ojima, Fumihiro; Matsue, Tomokazu; Osa, Tetsuo
Chemistry Letters, 1987 , p. 2235 - 2238
反应条件
1: 96 percent / conc. H2SO4 / CH2Cl2 / 15 h / Heating
2: 76 percent / diisopropylamine, n-BuLi / tetrahydrofuran; hexane / -78 °C
View Scheme
参考文献
Davis, Charles R.; Swenson, Dale C.; Burton, Donald J.
Journal of Organic Chemistry, 1993 , vol. 58, # 24 p. 6843 - 6850
反应条件
1: 80 percent / TiCl4, pyridine / CCl4; tetrahydrofuran / 60 h
2: 65 percent / L-selectride / tetrahydrofuran / 1.) -78 deg C, 2.) 0 deg C, 1 h
View Scheme
参考文献
Little, R. Daniel; Verhe, Roland; Monte, William T.; Nugent, Sean; Dawson, James R.
Journal of Organic Chemistry, 1982 , vol. 47, # 2 p. 362 - 364
反应条件
in N,N-dimethyl-formamide
-0.8 V (SCE), n-Bu4NBr;
参考文献
Nugent, Sean T.; Baizer, Manuel M.; Little, R. Daniel
Tetrahedron Letters, 1982 , vol. 23, # 13 p. 1339 - 1342
反应条件
Yield given. Multistep reaction;
参考文献
Hegedus,L.S.; Williams,R.E.; Mcguire,M.A.
Journal of the American Chemical Society, 1980 , vol. 102, p. 4973
反应条件
sulfuric acid; benzene
参考文献
Vogel
Journal of the Chemical Society, 1934 , p. 339
Journal of the Chemical Society, 1948 , p. 640
